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Ulcerative Colitis Clinical Trials Recruiting in the US

85 studies for Ulcerative Colitis are recruiting at 956 US sites, according to ClinicalTrials.gov data processed .

Ulcerative colitis is a type of inflammatory bowel disease that causes long-term inflammation and sores in the lining of the large intestine.

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Recruiting now

Top Ulcerative Colitis studies by number of US sites

Showing 30 studies, most US recruiting sites first.
  1. An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

    NCT07184996

    • Phase 3
    • Ages 16 to 80 years
    • Sex: All
    Recruiting sites
    117 US recruiting sites
  2. A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

    NCT06581328

    • Phase 4
    • Ages 18 to 80 years
    • Sex: All
    Recruiting sites
    78 US recruiting sites
  3. Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

    NCT07697456

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    60 US recruiting sites
  4. A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

    NCT07196748

    • Phase 3
    • Ages 12 years and older
    • Sex: All
    Recruiting sites
    51 US recruiting sites
  5. A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

    NCT07113522

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All
    Recruiting sites
    46 US recruiting sites
  6. Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

    NCT03816345

    • Phase 1
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    40 US recruiting sites
  7. LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

    NCT07415044

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All
    Recruiting sites
    39 US recruiting sites
  8. A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

    NCT06095128

    • Phase 4
    • Ages 18 to 65 years
    • Sex: All
    Recruiting sites
    37 US recruiting sites
  9. Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

    NCT06937086

    • Phase 3
    • Ages 18 to 70 years
    • Sex: All
    Recruiting sites
    37 US recruiting sites
  10. LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

    NCT07186101

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All
    Recruiting sites
    37 US recruiting sites
  11. Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

    NCT06619990

    • Phase 1/2
    • Ages 18 to 75 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    30 US recruiting sites
  12. A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

    NCT07185009

    • Phase 3
    • Ages 16 to 80 years
    • Sex: All
    Recruiting sites
    28 US recruiting sites
  13. A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

    NCT07012395

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    26 US recruiting sites
  14. An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

    NCT06398626

    • Observational
    • Ages 18 to 64 years
    • Sex: All
    Recruiting sites
    24 US recruiting sites
  15. A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis

    NCT07577856

    • Phase 3
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    24 US recruiting sites
  16. A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis

    NCT07845487

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    24 US recruiting sites
  17. Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

    NCT05230173

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    19 US recruiting sites
  18. BOOM-IBD2 Pivotal Clinical Trial

    NCT06571669

    • Interventional
    • Ages 18 to 85 years
    • Sex: All
    Recruiting sites
    16 US recruiting sites
  19. A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

    NCT05076175

    • Phase 2/3
    • Ages 2 to 17 years
    • Sex: All
    Recruiting sites
    12 US recruiting sites
  20. A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

    NCT05287126

    • Phase 2
    • Ages 12 to 17 years
    • Sex: All
    Recruiting sites
    12 US recruiting sites
  21. Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

    NCT05987852

    • Interventional
    • Ages 18 to 85 years
    • Sex: All
    Recruiting sites
    12 US recruiting sites
  22. Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

    NCT06651281

    • Phase 3
    • Ages Any age
    • Sex: All
    Recruiting sites
    12 US recruiting sites
  23. A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

    NCT07071519

    • Phase 3
    • Ages 2 to 17 years
    • Sex: All
    Recruiting sites
    12 US recruiting sites
  24. A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

    NCT07483073

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All
    Recruiting sites
    12 US recruiting sites
  25. Zymfentra (Infliximab-dyyb) REal World Cohort STudy

    NCT07237516

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    11 US recruiting sites
  26. A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

    NCT07463183

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    11 US recruiting sites
  27. A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis

    NCT06636656

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All
    Recruiting sites
    10 US recruiting sites
  28. A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

    NCT04844606

    • Phase 3
    • Ages 2 to 19 years
    • Sex: All
    Recruiting sites
    9 US recruiting sites
  29. A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

    NCT06979336

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    8 US recruiting sites
  30. A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis

    NCT07158242

    • Phase 3
    • Ages 2 to 17 years
    • Sex: All
    Recruiting sites
    8 US recruiting sites

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Ulcerative Colitis clinical trials by city

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining an Ulcerative Colitis clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.