LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
NCT07186101
This study is recruiting at 37 US sites in 19 states, according to its ClinicalTrials.gov record last updated .
Summary
The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compared to mirikizumab alone in adult participants with moderately to severely active ulcerative colitis (UC). Study participation will last approximately 118 weeks, including 104 weeks of treatment and may include up to 21 visits.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Ulcerative Colitis
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Eli Lilly and Company
- Last updated on ClinicalTrials.gov
- October 8, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 1
- Mayo Clinic in Arizona - Scottsdale · Scottsdale, AZ
California · 3
- Clinnova Research - Anaheim · Anaheim, CA
- Om Research LLC · Lancaster, CA
- Biopharma Informatic, LLC · Los Angeles, CA
Colorado · 1
- Peak Gastroenterology Associates · Colorado Springs, CO
Florida · 7
- NeoClinical Research · Hialeah, FL
- Encore Borland-Groover Clinical Research · Jacksonville, FL
- Clinical Research of Osceola · Kissimmee, FL
- Florida Research Institute · Lakewood Rch, FL
- Alliance Medical Research · Lighthouse PT, FL
- Atlantic Medical Research · Margate, FL
- Digestive and Liver Center of Florida · Orlando, FL
Illinois · 3
- Midtown Gastroenterology and Liver Disease · Des Plaines, IL
- GI Alliance - Glenview · Glenview, IL
- Gi Alliance - Gurnee · Gurnee, IL
Indiana · 1
- Gastroenterology Health Partners · New Albany, IN
Kentucky · 1
- Gastroenterology Health Partners · Louisville, KY
Massachusetts · 1
- Brigham and Women's Hospital · Boston, MA
Michigan · 1
- Clinical Research Institute of Michigan, LLC · Clinton Township, MI
Mississippi · 1
- GI Associates - GIA and Endoscopy Center - Flowood · Flowood, MS
New York · 1
- Digestive Disease Medicine of Central New York · Utica, NY
Ohio · 1
- Dayton Gastroenterology, LLC · Dayton, OH
Rhode Island · 1
- University Gastroenterology - Providence - West River Street · Providence, RI
South Carolina · 1
- Gastroenterology Associates, P.A. of Greenville · Greenville, SC
Tennessee · 1
- Gastro One - Walnut Run Road · Cordova, TN
Texas · 7
- Texas Digestive Disease Consultants - Cedar Park · Cedar Park, TX
- GI Alliance - Fort Worth · Fort Worth, TX
- GI Alliance - Garland · Garland, TX
- GI Alliance - Lubbock · Lubbock, TX
- Southern Star Research Institute · San Antonio, TX
- Tyler Research Institute · Tyler, TX
- GI Alliance-Webster · Webster, TX
Utah · 1
- Care Access - Ogden · Ogden, UT
Virginia · 3
- Clinical Research Partners, LLC · Richmond, VA
- GI Alliance - Richmond · Richmond, VA
- Carilion Clinic · Roanoke, VA
Washington · 1
- Washington Gastroenterology - Bellevue · Bellevue, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.