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ERP to Improve Functioning in Veterans With OCD

NCT05240924

This study is recruiting at 19 US sites in 8 states, according to its ClinicalTrials.gov record last updated .

Summary

Obsessive compulsive disorder (OCD) is a debilitating psychiatric illness impacting work, social, and family functioning. Exposure and Response Prevention (ERP) is the sole evidence-based psychotherapy for OCD; however, no randomized controlled trials (RCTs) have examined the effectiveness of ERP among Veterans or individuals with both OCD and posttraumatic stress disorder (PTSD). This 4-year Hybrid Type I trial will compare outcomes of ERP to those of a control condition among Veterans with OCD.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Obsessive Compulsive Disorder (OCD)
  • Comorbid Post-Traumatic Stress Disorder and OCD

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
VA Office of Research and Development
Last updated on ClinicalTrials.gov
June 8, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

New Jersey · 1

  • East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ · East Orange, NJ

New York · 4

  • VA Western New York Healthcare System, Buffalo, NY · Buffalo, NY
  • VA NY Harbor Healthcare System, New York, NY · New York, NY
  • Northport VA Medical Center, Northport, NY · Northport, NY
  • James J. Peters VA Medical Center, Bronx, NY · The Bronx, NY

North Carolina · 4

  • Asheville VA Medical Center, Asheville, NC · Asheville, NC
  • Durham VA Medical Center, Durham, NC · Durham, NC
  • Fayetteville VA Medical Center, Fayetteville, NC · Fayetteville, NC
  • Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC · Salisbury, NC

Oregon · 2

  • VA Roseburg Healthcare System, Roseburg, OR · Roseburg, OR
  • VA Southern Oregon Rehabilitation Center and Clinics, White City, OR · White City, OR

South Carolina · 1

  • Ralph H. Johnson VA Medical Center, Charleston, SC · Charleston, SC

Texas · 2

  • Michael E. DeBakey VA Medical Center, Houston, TX · Houston, TX
  • Michael E. DeBakey VA Medical Center, Houston, TX · Houston, TX

Virginia · 3

  • Hampton VA Medical Center, Hampton, VA · Hampton, VA
  • Hunter Holmes McGuire VA Medical Center, Richmond, VA · Richmond, VA
  • Salem VA Medical Center, Salem, VA · Salem, VA

Washington · 2

  • Spokane VA Medical Center, Spokane, WA · Spokane, WA
  • Jonathan M. Wainwright Memorial VA Medical Center, Walla Walla, WA · Walla Walla, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.