Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial
NCT05208190
This study is recruiting at 7 US sites in 5 states, according to its ClinicalTrials.gov record last updated .
Summary
Two-hundred and eighty individuals with schizophrenia who have a recent history of violent acts will be randomized in this 2-arm, parallel-group, 24-week, open-label, 7-site clinical trial to examine the effects of treatment with clozapine vs antipsychotic treatment as usual (TAU) for reducing the risk of violent acts in real-world settings
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Schizophrenia
- Schizoaffective Disorder
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 4
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- New York State Psychiatric Institute
- Last updated on ClinicalTrials.gov
- May 4, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 1
- University of California, Los Angeles · Los Angeles, CA
Georgia · 1
- Augusta University Research Institute, Inc. · Augusta, GA
Maryland · 1
- University of Maryland School of Medicine · Baltimore, MD
New York · 3
- Manhattan Psychiatric Center · New York, NY
- New York State Psychiatric Institute · New York, NY
- NYU Langone Medical Center · New York, NY
North Carolina · 1
- University of North Carolina at Chapel Hill · Chapel Hill, NC
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.