A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants
NCT07535034
This study is recruiting at 41 US sites in 17 states, according to its ClinicalTrials.gov record last updated .
Summary
The primary objective of this trial is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 in participants with gout who are XOI intolerant or have failed uricase treatment.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Gout
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 2
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Crystalys Therapeutics
- Last updated on ClinicalTrials.gov
- September 28, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- The Kirklin Clinic of UAB Hospital · Birmingham, AL
Arizona · 2
- Arizona Arthritis & Rheumatology Research, PLLC · Phoenix, AZ
- AARA Clinical Research-SE Tucson · Tucson, AZ
California · 3
- Amicis Research Center · Granada Hills, CA
- Cohen Medical Center · Thousand Oaks, CA
- Solace Clinical Research · Tustin, CA
Colorado · 1
- Denver Arthritis Clinic - Lowry · Denver, CO
Florida · 8
- Omega Research Group · DeBary, FL
- Herco Medical and Research Center, Inc · Flagami, FL
- New Generation of Medical Research · Hialeah, FL
- Health Awareness, Inc. · Jupiter, FL
- Clinical Research of Central Florida · Lakeland, FL
- D&H Pompano Research Center, LLC · Margate, FL
- Anchor Medical Research · Miami, FL
- Panax Clinical Research · Miami, FL
Georgia · 1
- Southwest Atlanta Internal Medicine · Atlanta, GA
Illinois · 1
- Great Lakes Clinical Trials · Chicago, IL
Kentucky · 1
- Research Group of Lexington, LLC · Lexington, KY
Maryland · 2
- MD Medical Research · Oxon Hill, MD
- AARA Clinical Research-Arthritis and Rheumatism Associates · Rockville, MD
Michigan · 3
- Clinical Research Institute of Michigan · Saint Clair Shores, MI
- Revival Research Institute · Sterling Heights, MI
- Oakland Medical Research Center · Troy, MI
Nebraska · 1
- Velocity Clinical Research · Norfolk, NE
Nevada · 1
- Las Vegas Clinical Trials · Las Vegas, NV
New Jersey · 1
- Premier Health Research · Sparta, NJ
New York · 2
- Ellipsis Research Group · Brooklyn, NY
- Drug Trials America · Hartsdale, NY
North Carolina · 2
- DJL Clinical Research · Charlotte, NC
- Shelby Clinical Research · Shelby, NC
Ohio · 1
- Hometown Urgent Care and Research · Dayton, OH
Texas · 10
- Amarillo Premier Research · Amarillo, TX
- Zenos Clinical Research · Dallas, TX
- Epic Medical Research · DeSoto, TX
- Pioneer Research Solutions · Houston, TX
- R&H Clinical Research - Westborough Drive · Katy, TX
- Southwest Rheumatology Research · Mesquite, TX
- Discovery Clinical Trials, LLC · San Antonio, TX
- DM Clinical Research · Tomball, TX
- Velocity Clinical Research (Impact Research Institute) · Waco, TX
- Digestive Health Research of North Texas · Wichita Falls, TX
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.