Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares

Summary

This is a randomized, multicenter, double-blind, single administration study to investigate the efficacy and safety of 2 dosing regimens of Purified Cortrophin® Gel in the treatment of an acute gouty arthritis flare. The study consists of three periods: an optional pre-screening period, a double-blind treatment period, and a 7-day follow-up period. The treatment period is double-blind, and the patients will be randomized to treatment with 40 U Purified Cortrophin® Gel or 80 U Purified Cortrophin® Gel in a 1:1 ratio.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Gout Arthritis
• Gout Flare
• Gout

Eligibility basics and study details

Study type

Interventional

Phase

Phase 4

Ages

18 to 90 years

Sex

All

Healthy volunteers

Not accepted

Sponsor

Massachusetts General Hospital

Last updated on ClinicalTrials.gov

January 20, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites