Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
NCT06891755
This study is recruiting at 18 US sites in 13 states, according to its ClinicalTrials.gov record last updated .
Summary
The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphysema suffering from dyspnea due to hyperinflation despite optimal medical treatment. The Apreo BREATHE Airway Scaffold is a permanent implant designed to tent open native airways. The study will include up to 250 participants at up to 25 study centers located in the United States and Europe. Study subjects will be followed for 3 years. The main questions it aims to answer are: Is it safe?
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- COPD
- Emphysema
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 40 to 84 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Apreo Health, Inc.
- Last updated on ClinicalTrials.gov
- April 24, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama at Birmingham · Birmingham, AL
Arizona · 1
- Banner Health · Gilbert, AZ
California · 1
- University of California at Davis · Sacramento, CA
Florida · 2
- Mayo Clinic · Jacksonville, FL
- Orlando Health · Orlando, FL
Illinois · 2
- University of Chicago · Chicago, IL
- OSF St Francis Medical Center · Peoria, IL
Kansas · 1
- University of Kansas Medical Center Research Institute · Kansas City, KS
Massachusetts · 1
- Beth Israel Deaconess Medical Center · Boston, MA
Michigan · 1
- University of Michigan · Ann Arbor, MI
Ohio · 2
- Cleveland Clinic Foundation · Cleveland, OH
- The Ohio State University · Columbus, OH
Pennsylvania · 3
- Clinical Research Associates of Central Pennsylvania · DuBois, PA
- Temple University · Philadelphia, PA
- University of Pittsburgh Medical Center · Pittsburgh, PA
Texas · 1
- Houston Methodist/Primary Critical Care · Houston, TX
Virginia · 1
- Inova Health Care Services · Falls Church, VA
Wisconsin · 1
- Medical College of Wisconsin · Milwaukee, WI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.