An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

Summary

This is a prospective, open-label, multi-center, single-arm study planned to enroll 200 subjects with heterogeneous emphysema and collateral ventilation (CV) in the target lobe. Subjects will undergo instillation of AeriSeal Foam in the target lobe and subsequent assessment of CV status using Chartis Pulmonary Assessment System. Subjects with CV- status will then undergo placement of Zephyr Valve in the target lobe for bronchoscopic lung volume reduction (BLVR) and be followed for 24 months.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Emphysema, Pulmonary
• Emphysema or COPD

Eligibility basics and study details

Study type

Interventional

Phase

Not applicable

Ages

40 to 80 years

Sex

All

Healthy volunteers

Not accepted

Sponsor

Pulmonx Corporation

Last updated on ClinicalTrials.gov

September 17, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites