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Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints

NCT05776056

This study is recruiting at 3 US sites in 2 states, according to its ClinicalTrials.gov record last updated .

Summary

Posttraumatic stress disorder (PTSD) is frequently accompanied by difficulty concentrating, poor memory, and inability to keep up with tasks, which negatively impacts a person's ability to function at work and in relationships. Currently available treatments do not fully relieve all symptoms. A published research report showed positive evidence that the stimulant medication methylphenidate was beneficial in treating these problems. This study will evaluate the ability of methylphenidate to treat PTSD and associated neurocognitive complaints in Veterans.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Posttraumatic Stress Disorder (PTSD)

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 to 65 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
VA Office of Research and Development
Last updated on ClinicalTrials.gov
August 19, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alabama · 2

  • Birmingham VA Medical Center, Birmingham, AL · Birmingham, AL
  • Tuscaloosa VA Medical Center, Tuscaloosa, AL · Tuscaloosa, AL

Washington · 1

  • VA Puget Sound Health Care System Seattle Division, Seattle, WA · Seattle, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.