SPIROMICS Study of Early COPD Progression (SOURCE)
NCT05033990
This study is recruiting at 14 US sites in 12 states, according to its ClinicalTrials.gov record last updated .
Summary
This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals: To use CT scan imaging to identify which smokers will develop COPD. To identify biomarkers predictive of smokers that will develop COPD. To determine if sputum (phlegm) can be analyzed to predict which smokers will develop COPD.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- COPD, Early-Onset
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 30 to 55 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- University of Massachusetts, Worcester
- Last updated on ClinicalTrials.gov
- June 3, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama at Birmingham · Birmingham, AL
Arizona · 1
- Mayo Clinic Arizona · Scottsdale, AZ
California · 2
- University of California Los Angeles · Los Angeles, CA
- University of California, San Francisco · San Francisco, CA
Colorado · 1
- National Jewish Health · Denver, CO
Illinois · 1
- University of Illinois Chicago · Chicago, IL
Iowa · 1
- University of Iowa · Iowa City, IA
Maryland · 1
- Johns Hopkins Bayview Medical Center · Baltimore, MD
Michigan · 1
- University of Michigan · Ann Arbor, MI
New York · 2
- Columbia University · New York, NY
- Weill Cornell Medical Center · New York, NY
North Carolina · 1
- Wake Forest · Winston-Salem, NC
Pennsylvania · 1
- Temple University · Philadelphia, PA
Utah · 1
- University of Utah · Salt Lake City, UT
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.